Hypothermic Machine Preservation of the Liver: State of the Art
نویسندگان
چکیده
Purpose of Review In this review, we highlight which livers may benefit from additional treatment before implantation and describe the concept of hypothermic machine liver perfusion. Furthermore, we explain why cold oxygenated perfusion concepts could potentially lead to a breakthrough in this challenging field of transplantation. Accordingly, we summarize recent clinical applications of different hypothermic perfusion approaches. Recent Findings The impact of end-ischemic, hypothermic liver perfusion in liver transplantation is currently assessed by two multicenter, randomized controlled trials. Recently, new applications of hypothermic perfusion showed promising results and recipients were protected from severe intrahepatic biliary complications, despite the use of very extended criteria grafts including donation after circulatory death livers. Summary Hypothermic machine liver perfusion is beneficial for high-risk livers and protects recipients from most feared complications. Importantly, such easy approach is currently implemented in several European centers and new markers obtained from perfusate may improve the prediction of liver function in the future.
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Correction to: Hypothermic Machine Preservation of the Liver: State of the Art
The article Hypothermic Machine Preservation of the Liver: State of the Art, written by Andrea Schlegel, Xavier Muller and Philipp Dutkowski, was originally published electronically on the publisher’s internet portal (currently SpringerLink) on January 22, 2018, without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed on February 2018 to © Th...
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عنوان ژورنال:
دوره 5 شماره
صفحات -
تاریخ انتشار 2018